January Virtual Journal Club: "Comparison of Dopamine and Norepinephrine in the Treatment of Shock"

N Engl J Med 2010; 362:779-789

Link to full Article: http://www.nejm.org/doi/full/10.1056/NEJMoa0907118#t=abstract

Host Commentary:  In my opinion, this has become somewhat of a "classic" Emergency Medicine article. It came out a few years ago and was offered as one of the LLSA review articles for 2012.  It is a comparison between dopamine and norepinephrine in the treatment of shock.  In general it concluded that dopamine was associated with more complications. Although I still find instances to use dopamine (for example when I don't have central line access) I find that norepinephrine is more frequently my preferred pressor.  

Questions:

1. This study was a ________ : 

a. Multicenter Observational study

b. Multicenter Randomized Trial

c. Single Center Cohort study

d. Single Center Case study

2. True or False: There was no significant difference in the primary endpoint (rate of death at 28 days)? 

a. True

b. False

3. Much of this study was based on the _______ study, an observational study which showed a 43% rate of death for Dopamine and a 36% rate of death for Norepinephrine.

a. DOPE

b. SOAP

c. HOPE

d. COPE

4.  There were more __________ events in the dopamine group as compared to the norepinephrine group. 

a. arrhythmic 

b. ischemic

c. tachypnic  

d. seismic

5. Subgroup analysis of dopamine use revealed an increased rate of death in which  form of shock: 

a. Cardogenic

b. Septic

c. Hypovolemic

d. Neurogenic 

Attention Allina Providers

For CME access the Allina SABA site using your Allina login and password.  
Then click on "My Learning" 
Then click on  "In Progress Learning" 
Find the Virtual Journal Club Entry Initiate the Session
Attest that you have read the article and complete the 5 question test. 
You will need to score 80% (4 of 5) to receive CME credit  
(Answers will be available upon completion of the quiz)
You should receive a certificate upon completion

Link Below: 

https://training.sabanow.net/Saba/Web/Main